PresenceofIrritableBowelSyndromeSymptomsinQuiescentInfammatoryBowelDiseaseIsAssociatedwithHighRateofAnxietyandDepression
炎症性肠病静息状态下存在的肠易激综合征症状与焦虑和抑郁症高发率的相关性
Abstract
Background:Infammatoryboweldisease(IBD;Crohn’sdisease,CDandUlcerativecolitis,UC)andirritablebowelsyndrome(IBS)haveoverlappingsymptoms.FewprevalencestudiesofIBSinquiescentIBDhaveusedcolonoscopywithhistologytoconfrminactivedisease.
背景:炎症性肠病(IBD)和肠易激综合征(IBS)具有重叠的症状。有关静息期IBD中IBS症状的流行病学研究显示很少通过结肠镜检查和组织学来治疗非活动期疾病。
Theaimswere(1)todeterminethepercentageofIBDpatientsindeepremissionwhosepersistentIBS-likesymptoms(IBD/IBS+)wouldcausethemtobeclassifedashavingactivedisease,basedonthecalculationofHarveyBradshawIndex(HBI)orUCdiseaseactivityindex(UCDAI);(2)toidentifydemographicanddiseasecharacteristicsthatareassociatedwithIBD/IBS+.
目的是(1)根据HBI或UC疾病活动指数计算确定IBD患者的深度缓解百分比,将其持续的IBS症状归类为活动期;(2)确定与IBD/IBS+相关的人口统计学和疾病特征。
Methods:
ThiswasaprospectivestudyatasingletertiarycareIBDcenter.96/patientswithcolonoscopyandhistologyconfrmedquiescentdiseaseconsentedand北京白癜风医院那个好北京中科白癜风医院圆梦征程